Feed aggregator

Nature, Published online: 20 February 2025; doi:10.1038/d41586-025-00207-y

Tracy Wietecha says the experience swallowed up evenings and weekends, but taught her budgeting, networking and conflict-management skills.

Nature, Published online: 20 February 2025; doi:10.1038/d41586-025-00528-y

‘One-shot’ approach that uses machine learning to screen immune cells could help to detect conditions with overlapping symptoms.

Nature, Published online: 20 February 2025; doi:10.1038/d41586-025-00540-2

The Trump administration is exploiting a loophole to keep a funding freeze in place, leaving researchers in limbo.

Nature, Published online: 20 February 2025; doi:10.1038/s41586-025-08782-w

Structural dynamics of human fatty acid synthase in the condensing cycle

Nature, Published online: 20 February 2025; doi:10.1038/s41586-025-08587-x

Using cryo-electron microscopy, the structures of mammalian fatty acid synthase reveal how the acyl carrier protein dynamically shuttles intermediates between selected active sites.

Nature, Published online: 20 February 2025; doi:10.1038/d41586-025-00525-1

The breakneck pace and devastating impact of the administration’s policy changes has shocked researchers.

Nature, Published online: 20 February 2025; doi:10.1038/d41586-025-00534-0

The child, who is now almost three years old, shows no signs of the often fatal motor neuron disease.

Nature, Published online: 19 February 2025; doi:10.1038/d41586-025-00535-z

Which universities top the retraction chart? Plus, meet the scientists editing Wikipedia in their spare time.

Nature, Published online: 19 February 2025; doi:10.1038/s41586-025-08776-8

Publisher Correction: Skin autonomous antibody production regulates host–microbiota interactions

Nature, Published online: 19 February 2025; doi:10.1038/s41586-024-08358-0

Reply to: Atlantic oceanic droughts do not threaten Asian water tower

Nature, Published online: 19 February 2025; doi:10.1038/s41586-025-08691-y

Author Correction: Seasonal advance of intense tropical cyclones in a warming climate

Nature, Published online: 19 February 2025; doi:10.1038/s41586-024-08357-1

Atlantic oceanic droughts do not threaten Asian water tower

Nature, Published online: 19 February 2025; doi:10.1038/d41586-025-00504-6

A catalyst that reduces usage of an expensive rare metal could help to make hydrogen fuel affordable.

Nature, Published online: 19 February 2025; doi:10.1038/s41586-024-08496-5

Insufficient evidence for natural selection associated with the Black Death

Nature, Published online: 19 February 2025; doi:10.1038/s41586-024-08267-2

Sequence clustering confounds AlphaFold2

Nature, Published online: 19 February 2025; doi:10.1038/s41586-024-08557-9

DNA double-strand breaks induce local genome maintenance and inhibition of replication initiation at nearby topologically associating domains without affecting global DNA synthesis.

Nature, Published online: 19 February 2025; doi:10.1038/s41586-025-08586-y

We show the evolution of a case of EGFR mutant lung cancer treated with a combination of erlotinib, osimertinib, radiotherapy and a personalized neopeptide vaccine targeting somatic mutations, including EGFR exon 19 deletion.

Nature, Published online: 19 February 2025; doi:10.1038/s41586-025-08600-3

A state-of-the-art generative artificial intelligence model of a video game is introduced to allow the support of human creative ideation, with the analysis of user study data highlighting three necessary capabilities, namely, consistency, diversity and persistency.

Nature, Published online: 19 February 2025; doi:10.1038/s41586-024-08508-4

In a phase 1 trial, patients with pancreatic ductal adenocarcinoma who were treated with surgery and bespoke neoantigen mRNA vaccines combined with anti-PD-L1 and chemotherapy exhibited marked long-lived persistence of neoantigen-specific CD8+ T cell clones, which correlated with prolonged recurrence-free survival at a 3.2-year follow-up.

Nature, Published online: 19 February 2025; doi:10.1038/s41586-025-08598-8

A study describes the design of de novo ligand-binding transmembrane proteins, demonstrating their specific binding and activation of fluorogenic ligands.