Controversial virus-hunting scientist skewered at US COVID-origins hearing
Nature, Published online: 01 May 2024; doi:10.1038/d41586-024-01305-z
Lawmakers interrogated Peter Daszak over his ties to China and whether his organisation, EcoHealth Alliance, has been a good steward of taxpayer dollars.A magnetic liquid makes for an injectable sensor in living tissue
Nature, Published online: 01 May 2024; doi:10.1038/d41586-024-01262-7
Fluid studded with microscopic magnetic particles can be inserted into the body and later retrieved.Pandemic lockdowns were less of a shock for people with fewer ties
Nature, Published online: 01 May 2024; doi:10.1038/d41586-024-01260-9
During periods of enforced isolation, life satisfaction for older adults took less of a hit in those who were already socially isolated.Found: the dial in the brain that controls the immune system
Nature, Published online: 01 May 2024; doi:10.1038/d41586-024-01259-2
Scientists identify the brain cells that regulate inflammation, and pinpoint how they keep tabs on the immune response.A body–brain circuit that regulates body inflammatory responses
Nature, Published online: 01 May 2024; doi:10.1038/s41586-024-07469-y
A body–brain circuit that regulates body inflammatory responsesMagnetic field effects on behaviour in <i>Drosophila</i>
Nature, Published online: 01 May 2024; doi:10.1038/s41586-024-07319-x
Magnetic field effects on behaviour in DrosophilaDad's microbiome can affect offsprings' health — in mice
Nature, Published online: 01 May 2024; doi:10.1038/d41586-024-01313-z
Disrupting gut microbes increases risk of growth issues in the next generation, and understanding geographic variations in cancer rates.Sex and gender discussions don't need to be toxic
Nature, Published online: 01 May 2024; doi:10.1038/d41586-024-01311-1
The science of sex and gender is too often misinterpreted and weaponized. Now, three experts cut through the misinformation in search of a positive future for this long-neglected area of researchMagnetic field responses in <i>Drosophila</i>
Nature, Published online: 01 May 2024; doi:10.1038/s41586-024-07320-4
Magnetic field responses in DrosophilaBassetto et al. reply
Nature, Published online: 01 May 2024; doi:10.1038/s41586-024-07321-3
Bassetto et al. replyPaternal microbiome perturbations impact offspring fitness
Nature, Published online: 01 May 2024; doi:10.1038/s41586-024-07336-w
Disturbances in the gut microbiota of male mice manifest as fitness defects in their offspring by affecting plancenta function, revealing a paternal gut–germline axis.Sleep pressure modulates single-neuron synapse number in zebrafish
Nature, Published online: 01 May 2024; doi:10.1038/s41586-024-07367-3
Synapses are gained during spontaneous or forced periods of wake and lost during sleep in a neuron-subtype-dependent manner in zebrafish.Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1
Nature, Published online: 01 May 2024; doi:10.1038/s41586-024-07374-4
A structural, biochemical and metabolomic analysis reveals the mechanistic basis for transport of extracellular choline and ethanolamine into cells by the human transport protein FLVCR1.Probing single electrons across 300-mm spin qubit wafers
Nature, Published online: 01 May 2024; doi:10.1038/s41586-024-07275-6
Using a cryogenic 300-mm wafer prober, a new approach for the testing of hundreds of industry-manufactured spin qubit devices at 1.6 K provides high-volume data on performance, allowing optimization of the complementary metal–oxide–semiconductor (CMOS)-compatible fabrication process.Airway hillocks are injury-resistant reservoirs of unique plastic stem cells
Nature, Published online: 01 May 2024; doi:10.1038/s41586-024-07377-1
In the lungs, recently identified epithelial structures known as hillocks can act as injury-resistant reservoirs of stem cells.Geographic variation of mutagenic exposures in kidney cancer genomes
Nature, Published online: 01 May 2024; doi:10.1038/s41586-024-07368-2
Whole-genome sequencing of 962 clear cell renal cell carcinomas from 11 countries shows geographic variations in somatic mutation profiles, including a mutational signature of unknown cause in 70% of cases from Japan.Mechanics of human embryo compaction
Nature, Published online: 01 May 2024; doi:10.1038/s41586-024-07351-x
Using micropipette aspiration on donated human embryos, cell surface tensions during compaction were mapped, indicating a role for defective cell contractility in poor quality embryos.Temporal dynamics of the multi-omic response to endurance exercise training
Nature, Published online: 01 May 2024; doi:10.1038/s41586-023-06877-w
Temporal multi-omic analysis of tissues from rats undergoing up to eight weeks of endurance exercise training reveals widespread shared, tissue-specific and sex-specific changes, including immune, metabolic, stress response and mitochondrial pathways.3D genomic mapping reveals multifocality of human pancreatic precancers
Nature, Published online: 01 May 2024; doi:10.1038/s41586-024-07359-3
Quantitative multimodal 3D reconstruction of human pancreatic tissue at single-cell resolution reveals a high burden of multifocal, genetically heterogeneous pancreatic intraepithelial neoplasias in the normal adult pancreas.Chromatin accessibility during human first-trimester neurodevelopment
Nature, Published online: 01 May 2024; doi:10.1038/s41586-024-07234-1
A study describes chromatin accessibility and paired gene expression across the entire developing human brain during the first trimester in the context of gene regulation and neurodevelopmental disease.