Why queasiness kills hunger: brain circuit identified
Nature, Published online: 18 April 2024; doi:10.1038/d41586-024-01037-0
Feelings of hunger, nausea and fullness seem to be governed by separate brain circuits, finds a study in mice.Nearly half of China’s major cities are sinking — some ‘rapidly’
Nature, Published online: 18 April 2024; doi:10.1038/d41586-024-01149-7
Millions of people in the country’s coastal lands might find their homes below sea level by 2120 owing to sinking and sea-level rise.Londoners see what a scientist looks like up close in 50 photographs
Nature, Published online: 18 April 2024; doi:10.1038/d41586-024-01156-8
Nature’s Where I Work images are being exhibited in the UK capital until June.Burnt remains of Maya royalty mark a dramatic power shift
Nature, Published online: 18 April 2024; doi:10.1038/d41586-024-01075-8
Finds in pyramid at Guatemalan site suggest that remains were disinterred and desecrated in a public ritual.Violent volcanoes have wracked Jupiter’s moon Io for billions of years
Nature, Published online: 18 April 2024; doi:10.1038/d41586-024-01138-w
Understanding the volcanic moon’s history could offer fresh insights into conditions on early Earth.AI’s keen diagnostic eye
Nature, Published online: 18 April 2024; doi:10.1038/d41586-024-01132-2
Powered by deep-learning algorithms, artificial intelligence systems could replace agents such as chemicals currently used to augment medical scans.Meet ‘goldene’: this gilded cousin of graphene is also one atom thick
Nature, Published online: 18 April 2024; doi:10.1038/d41586-024-01118-0
Sheets of gold might find use as catalysts, or in light-sensing devices.Daily briefing: Food is medicine
Nature, Published online: 17 April 2024; doi:10.1038/d41586-024-01153-x
Evidence is growing that targeted dietary interventions can treat, delay and even prevent some illnesses. Plus, an AI model helps track the spread of metastatic cancers and how climate lawsuits push governments and companies to act.This water bottle purifies your drink with energy from your steps
Nature, Published online: 17 April 2024; doi:10.1038/d41586-024-01074-9
Static electricity generated by the foot striking the ground can be captured to kill pathogens.Humans and their livestock have sheltered in this cave for 10,000 years
Nature, Published online: 17 April 2024; doi:10.1038/d41586-024-01131-3
Saudi Arabian herders have travelled the same routes for millennia, cave discovery suggests.Control of neuronal excitation–inhibition balance by BMP–SMAD1 signalling
Nature, Published online: 17 April 2024; doi:10.1038/s41586-024-07317-z
Signalling by the developmental morphogen BMP2 through the transcription factor SMAD1 has a key role in controlling the glutamatergic innervation of parvalbumin-expressing interneurons and maintaining the balance between excitation and inhibition in the mammalian cortex.Canadian science gets biggest boost to PhD and postdoc pay in 20 years
Nature, Published online: 17 April 2024; doi:10.1038/d41586-024-01124-2
Government budget includes more money for basic research and notable increases to postgraduate stipends.AI and robotics demystify the workings of a fly's wing
Nature, Published online: 17 April 2024; doi:10.1038/d41586-024-01122-4
New research unveils the workings of one of the most complex bio-mechanical structures in the natural worldDNA glycosylases provide antiviral defence in prokaryotes
Nature, Published online: 17 April 2024; doi:10.1038/s41586-024-07329-9
A screen utilizing an environmental DNA library in Escherichia coli is used to identify Brig1, a previously unknown anti-phage defence system with homologues across distinct clades of bacteria.Hybrid speciation driven by multilocus introgression of ecological traits
Nature, Published online: 17 April 2024; doi:10.1038/s41586-024-07263-w
Genomic studies of Heliconius butterflies provide evidence that Heliconius elevatus is a hybrid species, and that its speciation was driven by introgression of traits from Heliconius melpomene into the other parent, an ancestor of Heliconius pardalinus.Methane emission from a cool brown dwarf
Nature, Published online: 17 April 2024; doi:10.1038/s41586-024-07190-w
Methane emission from a very cool brown dwarf, perhaps arising from an aurora, has been detected in James Webb Space Telescope observations.Stepwise activation of a metabotropic glutamate receptor
Nature, Published online: 17 April 2024; doi:10.1038/s41586-024-07327-x
We propose a model for a sequential, multistep activation mechanism of metabotropic glutamate receptor subtype 5, including a series of structures in lipid nanodiscs, from inactive to fully active, with agonist-bound intermediate states.The economic commitment of climate change
Nature, Published online: 17 April 2024; doi:10.1038/s41586-024-07219-0
Analysis of projected sub-national damages from temperature and precipitation show an income reduction of 19% of the world economy within the next 26 years independent of future emission choices.Neural crest origin of sympathetic neurons at the dawn of vertebrates
Nature, Published online: 17 April 2024; doi:10.1038/s41586-024-07297-0
Challenging the belief that sympathetic ganglia are an innovation of jawed vertebrates, a study reports the presence of sympathetic neurons in an extant jawless vertebrate, the sea lamprey Petromyzon marinus.Refining the impact of genetic evidence on clinical success
Nature, Published online: 17 April 2024; doi:10.1038/s41586-024-07316-0
Human genetic evidence increases the success rate of drugs from clinical development to approval but we are still far from reaching peak genetic insights to aid the discovery of targets for more effective drugs.