Pig livers for people: US regulator greenlights first safety trial
Nature, Published online: 15 April 2025; doi:10.1038/d41586-025-01209-6
Four people with liver failure will be connected to an external organ from genetically modified pigs.Scientists must regain trust
Nature, Published online: 15 April 2025; doi:10.1038/d41586-025-01202-z
Scientists must regain trustDiscussions of technologies’ societal impacts are still too limited
Nature, Published online: 15 April 2025; doi:10.1038/d41586-025-01203-y
Discussions of technologies’ societal impacts are still too limitedAfrica CDC must become financially independent
Nature, Published online: 15 April 2025; doi:10.1038/d41586-025-01201-0
Africa CDC must become financially independentEarly air-pollution activists fight against city smoke
Nature, Published online: 15 April 2025; doi:10.1038/d41586-025-00918-2
A 250,000-year-old footprint preserved in ash, and the effect of a polluted atmosphere on health and the economy, in our weekly dip into Nature’s archive.Science’s golden oldies: the decades-old research papers still heavily cited today
Nature, Published online: 15 April 2025; doi:10.1038/d41586-025-01126-8
An analysis for Nature reveals the studies that appear most in the reference lists of current publications.These are the most-cited research papers of all time
Nature, Published online: 15 April 2025; doi:10.1038/d41586-025-01124-w
Some studies have received hundreds of thousands of citations, Nature’s updated analysis shows.The fight to keep big tech in check: digital researchers are in ‘David and Goliath’ battle
Nature, Published online: 15 April 2025; doi:10.1038/d41586-025-01141-9
Resource constraints hobble analyses of how digital technologies affect mental health, and take a huge toll on the scientists working to make the online world safer.High time to tackle drug-resistant fungal infections
Nature, Published online: 15 April 2025; doi:10.1038/d41586-025-01177-x
To combat long-overlooked fungal pathogens, researchers and regulators must embrace innovative science and policy.Exclusive: the most-cited papers of the twenty-first century
Nature, Published online: 15 April 2025; doi:10.1038/d41586-025-01125-9
A Nature analysis reveals the 25 highest-cited papers published this century and explores why they are breaking records.Richard Fortey obituary: palaeontologist, author and TV presenter who traced continents through fossils
Nature, Published online: 15 April 2025; doi:10.1038/d41586-025-01231-8
The fossil expert found love at first sight with trilobites.Twenty years of genome-wide association studies
Nature, Published online: 15 April 2025; doi:10.1038/d41586-025-01128-6
A powerful and unbiased way to identify links between genetic variants and biological traits has changed scientists’ understanding of complex diseases and how to treat them.Should I return to my home country after my PhD abroad?
Nature, Published online: 15 April 2025; doi:10.1038/d41586-025-01147-3
A graduate student from southeast Asia, now based in a European country and missing her homeland, agonizes over her next career move.Lung signals drive cancer-associated blood clots
Nature, Published online: 15 April 2025; doi:10.1038/d41586-025-01130-y
Fatal blood clots can arise in people who have cancer. The discovery of a cue that underlies these clots offers a therapeutic target and a way to assess clot risk.Daily briefing: Five lawsuits have been filed in response to NIH cuts — what now?
Nature, Published online: 14 April 2025; doi:10.1038/d41586-025-01222-9
Scientific bodies, academics and state attorneys have filed five lawsuits against the US National Institutes of Health, with more likely to follow. Plus, physicists have a new estimate for the maximum mass of a neutrino and a planet was spotted falling into its host star.Five key climate and space projects on Trump’s chopping block
Nature, Published online: 14 April 2025; doi:10.1038/d41586-025-01217-6
Leaked budget documents indicate which research programmes are at risk of being defunded in 2026.Prdm16-dependent antigen-presenting cells induce tolerance to gut antigens
Nature, Published online: 14 April 2025; doi:10.1038/s41586-025-08982-4
Prdm16-dependent antigen-presenting cells induce tolerance to gut antigensUnderstanding bones from the remote wilderness of Wyoming
Nature, Published online: 14 April 2025; doi:10.1038/d41586-025-01148-2
Digging in overlooked regions has opened up a world of discovery for palaeontologist David Lovelace.Radical approach to shrink particle colliders gains momentum
Nature, Published online: 14 April 2025; doi:10.1038/d41586-025-01181-1
Plans are taking off to use an unconventional technique to accelerate particles in a future collider.AI-boosted cameras help blind people to navigate
Nature, Published online: 14 April 2025; doi:10.1038/d41586-025-01214-9
A prototype wearable system uses machine-learning to guide users around obstacles.