Nature is the foremost international weekly scientific journal in the world and is the flagship journal for Nature Portfolio. It publishes the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature publishes landmark papers, award winning news, leading comment and expert opinion on important, topical scientific news and events that enable readers to share the latest discoveries in science and evolve the discussion amongst the global scientific community.
Updated: 31 min 11 sec ago
Using life cycle assessment to drive innovation for sustainable cool clouds
Nature, Published online: 30 April 2025; doi:10.1038/s41586-025-08832-3
A life cycle assessment study is used to examine the impacts of advanced cooling technologies on cloud infrastructure, from virtual machines to server architecture, data centre buildings and the grid.Selective inhibition of stromal mechanosensing suppresses cardiac fibrosis
Nature, Published online: 30 April 2025; doi:10.1038/s41586-025-08945-9
Inhibition of a cardiac stroma-enriched mechanosensor, SRC—in concert with suppression of the TGFβ pathway—potentiates the reversal of fibroblast activation and alleviates contractile dysfunction in fibrotic hearts.Serotonin and neurotensin inputs in the vCA1 dictate opposing social valence
Nature, Published online: 30 April 2025; doi:10.1038/s41586-025-08809-2
Aversive and rewarding social experiences are linked to conspecific identity through converging dorsal raphe 5-HT and paraventricular nucleus of the thalamus neurotensin signals in the vCA1 that instruct opposing valence, representing a synaptic switch for flexible social valence computation.A battery-free nanofluidic intracellular delivery patch for internal organs
Nature, Published online: 30 April 2025; doi:10.1038/s41586-025-08943-x
A nanofluidic intracellular delivery (NanoFLUID) patch provides a versatile, biocompatible and efficient method for the targeted delivery of payloads to internal organs for therapeutic purposes and for biomolecular investigations.An asymmetric fission island driven by shell effects in light fragments
Nature, Published online: 30 April 2025; doi:10.1038/s41586-025-08882-7
Measurements of fission fragments for 100 fissioning systems are used to map an asymmetric fission island, providing evidence for the role played by the deformation induced by a closed 36-proton shell.Single-cell transcriptomics reveal how root tissues adapt to soil stress
Nature, Published online: 30 April 2025; doi:10.1038/s41586-025-08941-z
Single-cell RNA sequencing and spatial transcriptomic approaches reveal major expression changes in outer root cell types when grown in soil versus gel conditions, and also uncover how root tissues communicate and adapt to contrasting soil conditions at single-cell resolution.Plant diversity dynamics over space and time in a warming Arctic
Nature, Published online: 30 April 2025; doi:10.1038/s41586-025-08946-8
Warming temperatures and interactions between plants are the main drivers of changes in Arctic plant communities in response to climate change, and there is no evidence of overall biotic homogenization.Sustainable nickel enabled by hydrogen-based reduction
Nature, Published online: 30 April 2025; doi:10.1038/s41586-025-08901-7
A one-step process using fossil-free hydrogen-plasma-based reduction is used to extract nickel from low-grade ore and create high-grade ferronickel alloys, providing a more sustainable and environmentally friendly method for obtaining nickel.Comparative connectomics of <i>Drosophila</i> descending and ascending neurons
Nature, Published online: 30 April 2025; doi:10.1038/s41586-025-08925-z
Three electron microscopy datasets are combined to provide a complete connectomic description of the neural circuitry that makes up the neck connective in Drosophila, including the descending neurons, ascending neurons and sensory ascending neurons.Observation of edge and bulk states in a three-site Kitaev chain
Nature, Published online: 30 April 2025; doi:10.1038/s41586-025-08892-5
An artificial Kitaev chain is realized by engineering three coupled quantum dots in a two-dimensional electron gas, which enables the manipulation and observation of both the edge and bulk states.The cell-division cycle is faster in cell types prone to forming cancer
Nature, Published online: 30 April 2025; doi:10.1038/d41586-025-01138-4
Some types of cell are more likely than others to give rise to tumours. A rapid cell cycle is a newly identified predictor of cancer susceptibility.Native American tribe teams up with genomicists to confirm link to iconic ancient site
Nature, Published online: 30 April 2025; doi:10.1038/d41586-025-01362-y
DNA from ancient and present-day members of Picuris Pueblo confirm oral histories linking the tribe to the famed Chaco Canyon centre.Inflammatory bowel disease has stages of epidemiology that can be tracked across global regions
Nature, Published online: 30 April 2025; doi:10.1038/d41586-025-01301-x
The spatio-temporal evolution of inflammatory bowel disease across the world follows four epidemiological stages: emergence, acceleration in incidence, compounding prevalence and prevalence equilibrium. Classifying regions by epidemiological stage enables health-care systems to prepare for the evolving global burden.Romeo and the robots
Nature, Published online: 30 April 2025; doi:10.1038/d41586-025-01278-7
A droid by any other name.Did a tardigrade get the world’s tiniest tattoo? April’s best science images
Nature, Published online: 30 April 2025; doi:10.1038/d41586-025-01320-8
The month’s sharpest science shots, selected by Nature’s photo team.Indigenous American tribe’s ancestral history confirmed by genomes
Nature, Published online: 30 April 2025; doi:10.1038/d41586-025-01304-8
Ancient and present-day genomes from members of the Indigenous American tribe Picuris Pueblo in the US Southwest show genetic continuity with Ancestral Pueblo individuals from the Chaco Canyon, New Mexico. These results confirm traditional knowledge and contest previous accounts that suggested that the population in the region collapsed before European colonization.How we call out the infuriating mistakes we spot in school science textbooks
Nature, Published online: 30 April 2025; doi:10.1038/d41586-025-00691-2
Two scientist parents who often help their children with homework deal with acceptable — and unacceptable — errors in course materials.Trump team’s science cuts threaten tenure hopes for early-career academics
Nature, Published online: 30 April 2025; doi:10.1038/d41586-025-01267-w
As funding dries up, US universities will need to reconsider traditional tenure requirements.Metal-cored molecule is the first of its kind
Nature, Published online: 30 April 2025; doi:10.1038/d41586-025-01135-7
A new class of organometallic compound has been made that has a distinctive geometry and electronic structure — with potential for catalysis and materials science.The end of AIDS is in sight: don’t abandon PEPFAR now
Nature, Published online: 30 April 2025; doi:10.1038/d41586-025-01308-4
The US administration should clear up the confusion over the future of a widely admired AIDS fund and push for Congress to reauthorize it.